Clinical Trial
A double-masked, randomized, controlled, multiple-dose study to evaluate the efficacy, safety, tolerability and systemic exposure of QR-110 in Subjects with Leber’s Congenital Amaurosis (LCA) due to c.2991+1655A>G mutation (p.Cys998X) in the CEP290 gene (Illuminate).
Disease
Disease type
Paediatric clinical trials
Orphan drug recognition
No
Patient type
Adult
Children
Inclusion / Exclusion
Funding
industry
Members involved
Others investigators
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/bart_leroy.jpg)
Pr Bart LEROY
Belgium
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/elfride_de_baere_2-1-scaled.jpg)
Pr Elfride DE BAERE
Belgium
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/carel-hoyng-1-230x230.jpg)
Pr Carel HOYNG
Netherlands
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/09/john-doe.jpg)
PD Dr Markus Preising
Germany
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/katarina_stingl.jpg)
Dr Katarina Stingl
Germany
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/MG_0650-scaled-e1706086196143-230x230-1.jpg)
Pr Isabelle Audo
France
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/helene_dollfus_2-230x230.jpg)
Pr Hélène Dollfus
France
ERN EYE member investigating site
HCP : Principal investigators
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/AdobeStock_615146071_Editorial_Use_Only-430x160.jpeg)
Ghent University Hospital, Ghent, Belgium
Adress
Corneel Heymanslaan 10
9000 Ghent
Belgium
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/images-275x160.jpg)
Radboud university medical center, Nijmegen, Netherlands
Adress
Geert Grooteplein Zuid 10
6525 GA Nijmegen
Netherlands
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/CON_534553936_M.jpg.33045795-430x160.jpg)
Universitätsklinikum Gießen und Marburg GmbH, Gießen, Germany
Adress
Klinik und Poliklinik für Augenheilkunde Friedrichstr. 18
35392 Gießen
Germany
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/tuebingen-430x160.jpg)
Centre for Ophthalmology, University Eye Hospital, Tübingen, Germany
Adress
Department für Augenheilkunde Tübingen Forschungsinstitut für Augenheilkunde Elfriede-Aulhorn-Str. 7
72076 Tübingen
Germany
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/images-262x160.jpeg)
CARGO, Hôpitaux Universitaires de Strasbourg, France
Adress
Hôpital Civil -Bâtiment du Centre de Recherche en Biomédecine de Strasbourg (CRBS),1 Rue Eugène Boeckel
67000 STRASBOURG
France
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/Quinze-Vingts-CHN03-430x160.jpg)
RÉFÉRET National Hospital of Ophthalmology of Quinze-Vingts, Paris, France
Adress
28 Rue de Charenton
75012 Paris
France