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Pr Carel HOYNG

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Member info

Pr Carel HOYNG

Representative

Netherlands

Working Group(s): Retinal Rare Eye Diseases (WG1), Genetic Diagnostics (TWG6), Registries & Epidemiology (TWG7), Research (TWG8)

Team

Pr Frans Cremers

Netherlands

Genetic Diagnostics (TWG6), Neuro-Ophthalmology Rare Diseases (WG2), Registries & Epidemiology (TWG7), Research (TWG8), Retinal Rare Eye Diseases (WG1)
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HCP Center

The main aim is to have a significant impact on healthcare. This mission is accomplished by:The Radboud university medical center (Radboudumc, in...

contact

Radboud university medical center, Nijmegen, Netherlands

Geert Grooteplein Zuid 10
6525 GA Nijmegen
Netherlands

Clinical trials

NCT05537220 Active, Not recruiting

NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients With Retinitis Pigmentosa

Interventional
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NCT05158296 Active, Not recruiting

A Double-Masked, Randomized, Controlled, Multiple-Dose Study to Evaluate the Efficacy, Safety and Tolerability of Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene (Sirius)

Interventional
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NCT05698316 Recruiting, Active

A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression: (INTERCEPT-AMD)

Observational
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NCT05633576 Completed

Steroid Eye Drops Versus Placebo Eye Drops in Chronic Central Serous Chorioretinopathy Trial (PICS Trial)

Interventional
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NCT04671433 Active, Not recruiting

Phase 3 Randomized, Controlled Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

Interventional
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NCT04794101 Active, Not recruiting

Phase 3 Follow-up Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

Interventional
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NCT04127006 Active, Not recruiting

Rate of Progression in EYS Related Retinal Degeneration (Pro-EYS).

Observational
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NCT03913143 Active, Not recruiting

A double-masked, randomized, controlled, multiple-dose study to evaluate the efficacy, safety, tolerability and systemic exposure of QR-110 in Subjects with Leber’s Congenital Amaurosis (LCA) due to c.2991+1655A>G mutation (p.Cys998X) in the CEP290 gene (Illuminate).

Interventional
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NCT03359551 Completed

Natural History of the Progression of Choroideremia Study NSR-CHM-OS1.

Observational
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NCT03146078 Active, Not recruiting

Rate of Progression in USH2A Related Retinal Degeneration

Observational
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NCT03584165 Recruiting, Active

A Long-term Follow-up Study to Evaluate the Safety and efficacy of Retinal Gene Therapy in Subjects with choroideremia treated previously with Adeno-Associated Viral Vector Encoding Rab Escort Protein-1 (AAV2-REP1) in an Antecedent Study.

Interventional
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NCT03079141 Unknown

Half-dose photodynamic therapy versus eplerenone treatment in chronic centralserous chorioretinopathy.

Interventional
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NCT02771379 Completed

A Non-interventional Study of Clinical Experience in Patients Prescribed Raxone® for the Treatment of Leber’s Hereditary Optic Neuropathy (LHON).

Observational
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NCT04770545 Active, Not recruiting

A Phase 3, Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Pegcetacoplan in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Interventional
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NCT04765345 Active, Not recruiting

Rate of Progression of PCDH15-Related Retinal Degeneration in Usher

Observational
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Scientific publications

Novel Clinical Observations and Genetic Spectrum in 340 Patients

In most patients, XLRS showed a slow deterioration starting in the second decade of life, suggesting an optimal window of opportunity for...

Outcome of Cataract Surgery in Patients With Retinitis Pigmentosa

To assess the visual outcome of cataract surgery in patients with retinitis pigmentosa...

The Natural History of Leber Congenital Amaurosis and ConeeRod Dystrophy Associated with Variants in the GUCY2D Gene

Leber congenital amaurosis associated with GUCY2D caused severe congenital visual impairment with relatively intact macular anatomy on funduscopy...

Repeatability of Quantitative Autofluorescence Imaging in a Multicenter Study Involving Patients With Recessive Stargardt Disease 1

Static Perimetry in the Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A) Study: Assessment Through 2 Years

Quantitative measures of SP declined significantly over 2 years in USH2A-related retinal...

Efficacy of Carbonic Anhydrase Inhibitors on Cystoid Fluid Collections and Visual Acuity in Patients with X-Linked Retinoschisis

Our data indicate that treatment with (oral) CAI may be beneficial for short-term management of CFC in patients with...

Central serous chorioretinopathy: Towards an evidence-based treatment guideline

To date, no consensus has been reached regarding the classification of CSC, and a wide variety of interventions have been proposed, reflecting the...