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Pr Frank Holz

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Member info

Pr Frank Holz

Representative

Germany

Team

Dr Philipp Herrmann

Germany

CPMS & Digital Medecine (TWG10), Genetic Diagnostics (TWG6), Research (TWG8), Retinal Rare Eye Diseases (WG1)
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HCP Center

The department for eye diseases covers the complete range of sugical ophthalmologic operations and offers care all state-of-the-art examination and...

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University of Bonn, Germany

Ernst-Abbe-Strasse 2
53127 Bonn
Germany

Clinical trials

NCT05698316 Recruiting, Active

A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression: (INTERCEPT-AMD)

Observational
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EST_2 - NCT01837901 Completed

Transcorneal Electrostimulation for Therapy of Retinitis Pigmentosa.

Interventional
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NCT01835002 Completed

This is a single-arm open label interventional safety trial with RP patients, who receive weekly TES for 6 months on 1 eye followed by observation for another 6 months without stimulation. The primary outcome measure is safety, indicated by the frequency and severity of adverse events.

Interventional
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2018-001496-20 Recruiting, Active

Clinical trials for A multi-national, multi-centre, double-masked, placebo-controlled proof of concept trial to evaluate the safety and efficacy of oral Soraprazan in Stargardt Phase 2, disease SMR-3438, Katairo

Interventional
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NCT03584165 Recruiting, Active

A Long-term Follow-up Study to Evaluate the Safety and efficacy of Retinal Gene Therapy in Subjects with choroideremia treated previously with Adeno-Associated Viral Vector Encoding Rab Escort Protein-1 (AAV2-REP1) in an Antecedent Study.

Interventional
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NCT02410122 Completed

The Natural History of the Progression of Atrophy Secondary to Stargardt Disease Type 4: PROM1-Related Macular Dystrophy (ProgStar-4).

Observational
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NCT05811351 Recruiting, Active

A Phase 2b, Randomized, Double-masked, Multicenter, Dose-ranging, Sham-controlled Clinical Trial to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Interventional
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NCT03364153 Active, Not recruiting

A Phase 2b Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of Zimura™ (Complement C5 Inhibitor) Compared to Sham in Subjects With Autosomal Recessive Stargardt Disease

Interventional
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NCT04435366 Completed

A Phase 3 Multicenter, Randomized, Double Masked, Sham- Controlled Clinical Trial to Assess the Safety and Efficacy of Intravitreal Administration of Zimura (Complement C5 Inhibitor) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Interventional
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NCT05384249 Recruiting, Active

A Phase 2b Pivotal Study to Evaluate the Efficacy and Safety of Izokibep in Subjects With Non-infectious, Intermediate-, Posterior- or Pan-uveitis

Interventional
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NCT03525600 Completed

A Phase 3, Multi-Center, Randomized, Double-Masked, Sham-Controlled Study to Compare the Efficacy and Safety of Intravitreal Pegcetacoplan Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

Interventional
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NCT04770545 Active, Not recruiting

A Phase 3, Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Pegcetacoplan in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Interventional
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DRKS00023562 Recruiting, Active

Evaluation of the effectiveness of transcorneal electrostimulation in patients with retinitis pigmentosa - a multicenter, prospective, randomized, controlled and double-blind study on behalf of the G-BA

Interventional
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NCT06070467 Not recruiting

Holistic Mixed Approaches to Capture the Real Life of Children With Rare Eye Diseases

Observational
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NCT04939571 Recruiting, Active

European Disease Registry on Retinopathy of Prematurity (ROP)

Observational
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