Member info
Pr Michael LARSEN
Denmark
Team
Dr Steffen HAMANN
Denmark
Line Kessel
Denmark
HCP Center
contact
Rigshospitalet, Copenhagen, Denmark
Clinical trials
A Phase 3, Randomized, International Multicenter Trial of DAY101 Monotherapy Versus Standard of Care Chemotherapy in Patients with Pediatric Low-Grade Glioma Harboring an Activating RAF Alteration Requiring First-Line Systemic Therapy
TENecteplase in Central Retinal Artery Occlusion Study (TenCRAOS): A Randomized Placebo-controlled Trial of Early Systemic Tenecteplase Treatment in Patients With Central Retinal Artery Occlusion.
This is a single-arm open label interventional safety trial with RP patients, who receive weekly TES for 6 months on 1 eye followed by observation for another 6 months without stimulation. The primary outcome measure is safety, indicated by the frequency and severity of adverse events.
Natural history of patients with inherited retinal diseases due to mutations in RPE65 gene
Safety and Efficacy of Emixustat in Stargardt Disease.
Efficacy and safety of QLT091001 in subjects with Inherited Retinal Disease (IRD) caused by gene mutations.
A Long-term Follow-up Study to Evaluate the Safety and efficacy of Retinal Gene Therapy in Subjects with choroideremia treated previously with Adeno-Associated Viral Vector Encoding Rab Escort Protein-1 (AAV2-REP1) in an Antecedent Study.
A Non-interventional Study of Clinical Experience in Patients Prescribed Raxone® for the Treatment of Leber’s Hereditary Optic Neuropathy (LHON).
Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT.
Clinical and Genetic Examination of Usher Syndrome Patients’ Cohort in Europe.
A Phase 2b, Randomized, Double-masked, Multicenter, Dose-ranging, Sham-controlled Clinical Trial to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Advanced Characterization of Autosomal Dominant Optic Atrophy.
Transcorneal Electrical Stimulation - Multicenter Safety Study.
Identification and Verification of Candidate Genes Responsible for Optic Disc Drusen
Non-Arteritic Anterior Ischemic Optic Neuropathy Risk Factors: New Perspectives
A Head-to-head Comparison of Ultrasound Versus Temporal Artery Biopsy in the Diagnosis of Giant Cell Arteritis
Global Patient Registry of Inherited Retinal Disease
Scientific publications
Multirater Validation of Peripapillary Hyperreflective Ovoid Mass-like Structures (PHOMS)
We performed a Delphi consensus process to develop a consistent and refined definition of PHOMS with clear principles around the nature of PHOMS...
Central serous chorioretinopathy: Towards an evidence-based treatment guideline
To date, no consensus has been reached regarding the classification of CSC, and a wide variety of interventions have been proposed, reflecting the...