Member info
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/catherine_vignal-230x230.jpg)
Dr Catherine Vignal-Clermont
France
HCP Center
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/11/AdobeStock_387658756_Editorial_Use_Only-430x160.jpeg)
contact
Fondation Adolphe de Rothschild, Paris, France
Clinical trials
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/08/ern-picto-500-230x230.jpg)
An open label dose escalation clinical trial to evaluate the safety and the tolerability of gs010 (rAAV2/2-ND4) in patients with leber hereditary optic neuropathy due to mutations in the mitochondrial nadh dehydrogenase 4 gene.
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/08/ern-picto-500-230x230.jpg)
A Non-interventional Study of Clinical Experience in Patients Prescribed Raxone® for the Treatment of Leber’s Hereditary Optic Neuropathy (LHON).
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/08/ern-picto-500-230x230.jpg)
Observational Registry Study of Leber Hereditary Optic Neuropathy (LHON) Affected Patients.
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/08/ern-picto-500-230x230.jpg)
Efficacy & Safety Study of Bilateral Intravitreal Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year (REFLECT).
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/08/ern-picto-500-230x230.jpg)
Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation.
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/08/ern-picto-500-230x230.jpg)
Long-term Follow-up of ND4 LHON Subjects Treated With GS010 Ocular Gene Therapy in the RESCUE or REVERSE Phase III Clinical Trials (RESTORE)
![](https://www.ern-eye.eu/wp-content/uploads/sites/2/2023/08/ern-picto-500-230x230.jpg)
Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation.