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ERDERA Joint Transnational Call for Proposals on Rare Disease Therapies

The European Rare Diseases Research Alliance (ERDERA) launched its Joint Transnational Call (JTC) for Proposals 2025 on December 10, 2024. This call invites research teams from across Europe and beyond to submit collaborative projects focused on “Pre-clinical therapy studies for rare diseases using small molecules and biologicals – development and validation”.

Topics of Interest

Eligible proposals may include research on:

  • Development of pre-clinical therapies using cell, organoid, or animal models.
  • Biomarker identification that correlates with therapeutic efficacy.
  • Pre-clinical proof-of-concept studies showing pharmacological activity and safety data.

Notably, gene therapies, rare neurodegenerative diseases like Alzheimer’s, and rare cancers are excluded from this call. Projects should have a special focus on therapies that can translate into clinical applications.

Application Timeline

The JTC 2025 will follow a two-stage submission process:

13 February 2025Deadline for pre-proposal submission
9 June 2025Deadline for full-proposal submission. Funding decisions are expected by December 2025.

EP PerMed JTC2025 Pre-announcement – Pharmacogenomic Strategies for Personalised Medicine (PGxPM2025)

The European Partnership for Personalised Medicine, EP PerMed (supported by the European Union under Horizon Europe, Grant Agreement N° 101137129), is a platform for joint programming of national and European regional research and innovation supporting activities putting into action “The Strategic Research & Innovation Agenda (SRIA) for Personalised Medicine (2023)” , SRIA for PM (2023), through dedicated research, development and innovation funding.

EP PerMed funding organisations have agreed to launch the joint transnational call 2025 (JTC2025), co-funded by the EU, to fund multinational innovative research projects in personalised medicine (PM), which should bring together academic, clinical/public health and private research teams, thus enhancing the competitiveness in Europe in this field. The JTC2025 will be conducted simultaneously by the participating funding organisations in their respective region/country and coordinated centrally by the Joint Call Secretariat (JCS), hosted by the German Aerospace Center e.V. – Project Management Agency, (DLR-PT), Germany.

The call will be implemented in two stages, i.e. a pre- and a full-proposal phase. The available budget for this call is 35 Mio. € (approx.).

An information day introducing the JTC2025 to the research community will be organised most probably on January 09, 2025. More details (including the registration) will follow soon.

18 February 2025 (14:00 CET)Deadline for pre-proposal submission
17 June 2025 (14:00, CEST)Deadline for full-proposal submission

IHI call 10 & 11

Call 10

The submission deadline for short proposals (SPs) will be 23 April 2025 and the full proposals (FPs) submission deadline will be 14 October 2025.

Topics:

  • Digital label: one source of comprehensive information for medical technology products
  • Enabling and safeguarding innovation in secondary use of health data in the European Health Data Space (EHDS)
  • Per- and Poly-fluoroalkyl substance (PFAS) exposure, emissions, and end of life management in the healthcare sector
23 April 2025Deadline for short proposal submission
14 October 2025Deadline for full-proposal submission

Call 11

The following topics are under consideration for inclusion in IHI call 11, a two-stage call which is scheduled for launch in Q2 2025:

Establishing ortho and cardiology ambulatory surgical centres in Europe


Calls of the European Commission

Please find here the links to calls of the European Commission you can apply to: