Informações do membro
Pr Carel HOYNG
Nederland
Centro de saúde
Contacto
Radboud university medical center, Nijmegen, Netherlands
Ensaios clínicos
NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients With Retinitis Pigmentosa
A Double-Masked, Randomized, Controlled, Multiple-Dose Study to Evaluate the Efficacy, Safety and Tolerability of Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene (Sirius)
A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression: (INTERCEPT-AMD)
Steroid Eye Drops Versus Placebo Eye Drops in Chronic Central Serous Chorioretinopathy Trial (PICS Trial)
Phase 3 Randomized, Controlled Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Phase 3 Follow-up Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Rate of Progression in EYS Related Retinal Degeneration (Pro-EYS).
A double-masked, randomized, controlled, multiple-dose study to evaluate the efficacy, safety, tolerability and systemic exposure of QR-110 in Subjects with Leber’s Congenital Amaurosis (LCA) due to c.2991+1655A>G mutation (p.Cys998X) in the CEP290 gene (Illuminate).
Safety and Efficacy of Emixustat in Stargardt Disease.
Natural History of the Progression of Choroideremia Study NSR-CHM-OS1.
Rate of Progression in USH2A Related Retinal Degeneration
A Long-term Follow-up Study to Evaluate the Safety and efficacy of Retinal Gene Therapy in Subjects with choroideremia treated previously with Adeno-Associated Viral Vector Encoding Rab Escort Protein-1 (AAV2-REP1) in an Antecedent Study.
Half-dose photodynamic therapy versus eplerenone treatment in chronic centralserous chorioretinopathy.
A Non-interventional Study of Clinical Experience in Patients Prescribed Raxone® for the Treatment of Leber’s Hereditary Optic Neuropathy (LHON).
A Phase 3, Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Pegcetacoplan in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher
Natural history of the progression of X-linked retinitis pigmentosa.
Characterizing Rate of Progression in USHer Syndrome (CRUSH) Study
A multi-national, multi-centre, double-masked, placebo-controlled proof of concept trial to evaluate the safety and efficacy of oral soraprazan in Stargardt disease
Publicações científicas
Novel Clinical Observations and Genetic Spectrum in 340 Patients
Na maioria dos pacientes, a XLRS mostrou uma deterioração lenta a partir da segunda década de vida, sugerindo uma janela de oportunidade ideal para...
Outcome of Cataract Surgery in Patients With Retinitis Pigmentosa
Avaliar o resultado visual da cirurgia de catarata em pacientes com retinite pigmentosa...
The Natural History of Leber Congenital Amaurosis and ConeeRod Dystrophy Associated with Variants in the GUCY2D Gene
A amaurose congênita de Leber associada ao GUCY2D causou grave deficiência visual congênita com anatomia macular relativamente intacta na fundoscopia...
Repeatability of Quantitative Autofluorescence Imaging in a Multicenter Study Involving Patients With Recessive Stargardt Disease 1
Static Perimetry in the Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A) Study: Assessment Through 2 Years
As medidas quantitativas de SP diminuíram significativamente ao longo de 2 anos na retina relacionada com USH2A...
Efficacy of Carbonic Anhydrase Inhibitors on Cystoid Fluid Collections and Visual Acuity in Patients with X-Linked Retinoschisis
Nossos dados indicam que o tratamento com CAI (oral) pode ser benéfico para o manejo de curto prazo do CFC em pacientes com...
Central serous chorioretinopathy: Towards an evidence-based treatment guideline
Até à data, não se chegou a um consenso relativamente à classificação da CSC, tendo sido propostas uma grande variedade de intervenções, reflectindo...