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Pr Frank Holz

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Alemanha

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Dr Philipp Herrmann

Alemanha

CPMS e medicina digital (TWG10), diagnóstico genético (TWG6), pesquisa (TWG8), doenças oculares raras da retina (WG1)
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Centro de saúde

O departamento de doenças oculares cobre toda a gama de operações oftalmológicas cirúrgicas e oferece atendimento de todos os exames e exames de última geração...

Contacto

University of Bonn, Germany

Ernst-Abbe-Strasse 2
53127 Bonn
Germany

Ensaios clínicos

NCT05698316). Recrutamento, Ativo

A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression: (INTERCEPT-AMD)

Observacional
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NCT01835002). Efetuado

This is a single-arm open label interventional safety trial with RP patients, who receive weekly TES for 6 months on 1 eye followed by observation for another 6 months without stimulation. The primary outcome measure is safety, indicated by the frequency and severity of adverse events.

Intervencionista
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2018-001496-20 Recrutamento, Ativo

Clinical trials for A multi-national, multi-centre, double-masked, placebo-controlled proof of concept trial to evaluate the safety and efficacy of oral Soraprazan in Stargardt Phase 2, disease SMR-3438, Katairo

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NCT03584165). Recrutamento, Ativo

A Long-term Follow-up Study to Evaluate the Safety and efficacy of Retinal Gene Therapy in Subjects with choroideremia treated previously with Adeno-Associated Viral Vector Encoding Rab Escort Protein-1 (AAV2-REP1) in an Antecedent Study.

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NCT02410122). Efetuado

The Natural History of the Progression of Atrophy Secondary to Stargardt Disease Type 4: PROM1-Related Macular Dystrophy (ProgStar-4).

Observacional
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NCT05811351). Recrutamento, Ativo

A Phase 2b, Randomized, Double-masked, Multicenter, Dose-ranging, Sham-controlled Clinical Trial to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Intervencionista
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NCT03364153). Ativo, não recrutando

A Phase 2b Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of Zimura™ (Complement C5 Inhibitor) Compared to Sham in Subjects With Autosomal Recessive Stargardt Disease

Intervencionista
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NCT04435366). Efetuado

A Phase 3 Multicenter, Randomized, Double Masked, Sham- Controlled Clinical Trial to Assess the Safety and Efficacy of Intravitreal Administration of Zimura (Complement C5 Inhibitor) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

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NCT05384249). Recrutamento, Ativo

A Phase 2b Pivotal Study to Evaluate the Efficacy and Safety of Izokibep in Subjects With Non-infectious, Intermediate-, Posterior- or Pan-uveitis

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NCT03525600). Efetuado

A Phase 3, Multi-Center, Randomized, Double-Masked, Sham-Controlled Study to Compare the Efficacy and Safety of Intravitreal Pegcetacoplan Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

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NCT04770545). Ativo, não recrutando

A Phase 3, Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Pegcetacoplan in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Intervencionista
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DRKS00023562 Recrutamento, Ativo

Evaluation of the effectiveness of transcorneal electrostimulation in patients with retinitis pigmentosa - a multicenter, prospective, randomized, controlled and double-blind study on behalf of the G-BA

Intervencionista
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NCT06070467). Não recrutando

Holistic Mixed Approaches to Capture the Real Life of Children With Rare Eye Diseases

Observacional
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