Ledeninformatie
Pr Carel HOYNG
Nederland
Team
Pr Frans Cremers
Nederland
HCP-centrum
contact
Radboud university medical center, Nijmegen, Netherlands
Klinische proeven
NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients With Retinitis Pigmentosa
A Double-Masked, Randomized, Controlled, Multiple-Dose Study to Evaluate the Efficacy, Safety and Tolerability of Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene (Sirius)
A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression: (INTERCEPT-AMD)
Steroid Eye Drops Versus Placebo Eye Drops in Chronic Central Serous Chorioretinopathy Trial (PICS Trial)
Phase 3 Randomized, Controlled Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Phase 3 Follow-up Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Rate of Progression in EYS Related Retinal Degeneration (Pro-EYS).
A double-masked, randomized, controlled, multiple-dose study to evaluate the efficacy, safety, tolerability and systemic exposure of QR-110 in Subjects with Leber’s Congenital Amaurosis (LCA) due to c.2991+1655A>G mutation (p.Cys998X) in the CEP290 gene (Illuminate).
Safety and Efficacy of Emixustat in Stargardt Disease.
Natural History of the Progression of Choroideremia Study NSR-CHM-OS1.
Rate of Progression in USH2A Related Retinal Degeneration
A Long-term Follow-up Study to Evaluate the Safety and efficacy of Retinal Gene Therapy in Subjects with choroideremia treated previously with Adeno-Associated Viral Vector Encoding Rab Escort Protein-1 (AAV2-REP1) in an Antecedent Study.
Half-dose photodynamic therapy versus eplerenone treatment in chronic centralserous chorioretinopathy.
A Non-interventional Study of Clinical Experience in Patients Prescribed Raxone® for the Treatment of Leber’s Hereditary Optic Neuropathy (LHON).
A Phase 3, Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Pegcetacoplan in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher
Natural history of the progression of X-linked retinitis pigmentosa.
Characterizing Rate of Progression in USHer Syndrome (CRUSH) Study
Wetenschappelijke publicaties
Novel Clinical Observations and Genetic Spectrum in 340 Patients
Bij de meeste patiënten vertoonde XLRS een langzame verslechtering vanaf het tweede levensdecennium, wat erop wijst dat er een optimale kans is voor...
Outcome of Cataract Surgery in Patients With Retinitis Pigmentosa
Om het visuele resultaat van een cataractoperatie bij patiënten met retinitis pigmentosa te beoordelen...
The Natural History of Leber Congenital Amaurosis and ConeeRod Dystrophy Associated with Variants in the GUCY2D Gene
Leber congenitale amaurose geassocieerd met GUCY2D veroorzaakte ernstige aangeboren visuele beperking met relatief intacte maculaire anatomie op funduscopie...
Repeatability of Quantitative Autofluorescence Imaging in a Multicenter Study Involving Patients With Recessive Stargardt Disease 1
Static Perimetry in the Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A) Study: Assessment Through 2 Years
Kwantitatieve metingen van SP zijn in twee jaar tijd aanzienlijk afgenomen in USH2A-gerelateerde retinale...
Efficacy of Carbonic Anhydrase Inhibitors on Cystoid Fluid Collections and Visual Acuity in Patients with X-Linked Retinoschisis
Onze gegevens geven aan dat behandeling met (orale) CAI gunstig kan zijn voor de kortetermijnbehandeling van CFK bij patiënten met...
Central serous chorioretinopathy: Towards an evidence-based treatment guideline
Tot op heden is er geen consensus bereikt over de classificatie van CSC, en er is een grote verscheidenheid aan interventies voorgesteld, die de...