Biedru informācija
Pr Carel HOYNG
Nīderlande
Komanda
Dr Lonneke HAER-WIGMAN
Nīderlande
HCP centrs
kontakts
Radboud university medical center, Nijmegen, Netherlands
Klīniskie izmēģinājumi
NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients With Retinitis Pigmentosa
A Double-Masked, Randomized, Controlled, Multiple-Dose Study to Evaluate the Efficacy, Safety and Tolerability of Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene (Sirius)
A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression: (INTERCEPT-AMD)
Steroid Eye Drops Versus Placebo Eye Drops in Chronic Central Serous Chorioretinopathy Trial (PICS Trial)
Phase 3 Randomized, Controlled Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Phase 3 Follow-up Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Rate of Progression in EYS Related Retinal Degeneration (Pro-EYS).
A double-masked, randomized, controlled, multiple-dose study to evaluate the efficacy, safety, tolerability and systemic exposure of QR-110 in Subjects with Leber’s Congenital Amaurosis (LCA) due to c.2991+1655A>G mutation (p.Cys998X) in the CEP290 gene (Illuminate).
Safety and Efficacy of Emixustat in Stargardt Disease.
Natural History of the Progression of Choroideremia Study NSR-CHM-OS1.
Rate of Progression in USH2A Related Retinal Degeneration
A Long-term Follow-up Study to Evaluate the Safety and efficacy of Retinal Gene Therapy in Subjects with choroideremia treated previously with Adeno-Associated Viral Vector Encoding Rab Escort Protein-1 (AAV2-REP1) in an Antecedent Study.
Half-dose photodynamic therapy versus eplerenone treatment in chronic centralserous chorioretinopathy.
A Non-interventional Study of Clinical Experience in Patients Prescribed Raxone® for the Treatment of Leber’s Hereditary Optic Neuropathy (LHON).
A Phase 3, Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Pegcetacoplan in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher
Natural history of the progression of X-linked retinitis pigmentosa.
Characterizing Rate of Progression in USHer Syndrome (CRUSH) Study
A multi-national, multi-centre, double-masked, placebo-controlled proof of concept trial to evaluate the safety and efficacy of oral soraprazan in Stargardt disease
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants
A Double-Masked, Randomized, Placebo-Controlled, Paired-Eye Study to Evaluate the Efficacy, Safety and Tolerability of Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Due to the c.2991+1655A>G (p.Cys998X) Mutation in the CEP290 Gene
Zinātniskās publikācijas
Novel Clinical Observations and Genetic Spectrum in 340 Patients
Lielākajai daļai pacientu XLRS uzrādīja lēnu pasliktināšanos, sākot ar otro dzīves desmitgadi, kas liecina par optimālu iespēju...
Outcome of Cataract Surgery in Patients With Retinitis Pigmentosa
Novērtēt kataraktas operācijas vizuālo iznākumu pacientiem ar pigmentozo retinītu...
The Natural History of Leber Congenital Amaurosis and ConeeRod Dystrophy Associated with Variants in the GUCY2D Gene
Lēbera iedzimtā amauroze, kas saistīta ar GUCY2D, funduskopijā izraisīja smagus iedzimtus redzes traucējumus ar salīdzinoši neskartu makulas anatomiju...
Repeatability of Quantitative Autofluorescence Imaging in a Multicenter Study Involving Patients With Recessive Stargardt Disease 1
Static Perimetry in the Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A) Study: Assessment Through 2 Years
SP kvantitatīvie rādītāji ievērojami samazinājās 2 gadu laikā ar USH2A saistītajā tīklenē...
Efficacy of Carbonic Anhydrase Inhibitors on Cystoid Fluid Collections and Visual Acuity in Patients with X-Linked Retinoschisis
Mūsu dati liecina, ka ārstēšana ar (orālo) CAI var būt noderīga īslaicīgai CFC ārstēšanai pacientiem ar...
Central serous chorioretinopathy: Towards an evidence-based treatment guideline
Līdz šim nav panākta vienprātība par CSC klasifikāciju, un ir ierosināti dažādi iejaukšanās pasākumi, kas atspoguļo...