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Clinical trials ongoing in ERN-EYE Members Expertise Centers

by disease

 You can click on the title of the trial to open a description of the trial

 

 

Guidance on the management of clinical trials during the COVID-19 (coronavirus) pandemic



Retinal Rare Eye Diseases (WG1)

Leber Congenital Amaurosis

Skin-to-Eye Study

NCT03359551

Choroideremia

Night

NCT03975543

Retinitis Pigmentosa, Pediatric clinical trials

PHENOROD1

NCT02671539

Choroideremia

THOR

NCT02110225

Retinitis Pigmentosa

LUMOS

NCT03490019

Bardet-Biedl, Pediatric clinical trials

BBS

NCT04405882

Hereditary retinal disease

Cornea Ectasia Excimer Laser Treatment

NCT02771236

Hereditary retinal disease, Pediatric clinical trials

Clinical and Molecular Studies in Families With Inherited Eye Disease

NCT03662386

Hereditary retinal disease, Pediatric clinical trials

GEPHIRD

NCT03772665

Stargardt Disease, Pediatric clinical trials

SeaSTAR

NCT01496040

Leber Congenital Amaurosis, Pediatric clinical trials

Clinical Gene Therapy Protocol for the Treatment of Retinal Dystrophy Caused by Defects in RPE65

NCT03913143

Leber Congenital Amaurosis, Pediatric clinical trials

ILLUMINATE

NCT03116113

Retinitis Pigmentosa, Pediatric clinical trials

XIRIUS

Leber Congenital Amaurosis

GENPHENACL

NCT01521793

Retinitis Pigmentosa, Leber Congenital Amaurosis, Pediatric clinical trials

RET IRD 02

NCT02575430

Leber Congenital Amaurosis, Pediatric clinical trials

RET NAT 01

NCT02410122

Stargardt Disease

PROGSTAR-4 STUDY

NCT02890550

Alström Syndrome, Pediatric clinical trials

Clinical Study of a single ciliopathy: Alström Syndrome

NCT03496012

Choroideremia

STAR

NCT01461213

Choroideremia

CIL 34546-NSR-REP-01

NCT01505062

Retinitis Pigmentosa, Usher Syndrome, Pediatric clinical trials

Study of UshStat in Patients With Retinitis Pigmentosa Associated With Usher Syndrome Type 1B

NCT01835002

Retinitis Pigmentosa

TESOLA

NCT03963154

Retinitis Pigmentosa

STREAM

NCT03326336

Retinitis Pigmentosa

PIONEER

NCT03780257

Retinitis Pigmentosa

STELLAR

NCT04128150

Other, Pediatric clinical trials

High Resolution Retina Imaging (IHR)

CURETINA

Hereditary retinal disease, Pediatric clinical trials

CURETINA

RET-IRD-04

Leber Congenital Amaurosis

RET-IRD-04

LIGHT4DEAF

Usher Syndrome, Pediatric clinical trials

LIGHT4DEAF

VITAL

Retinitis Pigmentosa, Pediatric clinical trials

VITAL

VITAL

Usher Syndrome, Pediatric clinical trials

VITAL

NCT01954953

Usher Syndrome, Pediatric clinical trials

EURUSH

NCT03297515

Stargardt Disease

MADEOS

NCT03507686

Choroideremia

Gemini

NCT03584165

Choroideremia

SOLSTICE

DIIO_EPPR_P13_03

Retinitis Pigmentosa, Pediatric clinical trials

Retinitis pigmentosa: molecular diagnosis by next generation sequencing

EudraCT 2016-003705-34

Retinitis Pigmentosa

PIGMENT – PDE6A gene therapy for retinitis pigmentosa

NCT04285398

Retinitis Pigmentosa

PHENOROD2

NCT02610582

CNGA3-linked achromatopsia

CNGA3

NCT03940690

Other, Pediatric clinical trials

COATS-VEGF

NCT00481546

Hereditary retinal disease, Pediatric clinical trials

LCA

NCT03913130

Leber Congenital Amaurosis, Pediatric clinical trials

INSIGHT

TESOLAUK - NCT01847365

Retinitis Pigmentosa

TES for the Treatment of Retinitis Pigmentosa (RP)

NCT00407602

Other, Pediatric clinical trials

Argus® II Retinal Stimulation System Feasibility Protocol

NCT03146078

Retinitis Pigmentosa, Usher Syndrome, Pediatric clinical trials

RUSH2A

REGENERATE - NCT02407678

Choroideremia

REP1 Gene Replacement Therapy for Choroideremia

NCT03780257

Usher Syndrome

STELLAR

NCT00407602

Retinitis Pigmentosa, Pediatric clinical trials

Argus® II Retinal Stimulation System Feasibility Protocol

NCT03314207

Retinitis Pigmentosa

XOLARIS

NCT03814499

Usher Syndrome, Pediatric clinical trials

Natural History Study in Subjects With Usher Syndrome

NCT03079141

Chorioretinopathy, Pediatric clinical trials

SPECT

NCT02521311

Hereditary retinal disease

RECOVER



Neuro-Ophthalmology Rare Diseases (WG2)

NCT01265719

Glaucoma, Pediatric clinical trials

LYNX

NCT02176733

Leber Hereditary Optic Neuropathy (LHON)

CICLO-NOHL

NCT01522638

Other, Pediatric clinical trials

ADOA

NCT02771379

Leber Hereditary Optic Neuropathy (LHON)

PAROS

NCT01892943

Leber Hereditary Optic Neuropathy (LHON), Pediatric clinical trials

Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey

NCT03293524

Leber Hereditary Optic Neuropathy (LHON)

REFLECT

NCT02796274

Leber Hereditary Optic Neuropathy (LHON), Pediatric clinical trials

Historical Case Record Survey of Visual Acuity Data From Patients With Leber’s Hereditary Optic Neuropathy (LHON)

NCT04561466

Leber Hereditary Optic Neuropathy (LHON)

BÉFINOHL

NCT03295071

Leber Hereditary Optic Neuropathy (LHON), Pediatric clinical trials

REALITY

NCT02652767

Leber Hereditary Optic Neuropathy (LHON)

RESCUE

NCT02652780

Leber Hereditary Optic Neuropathy (LHON), Pediatric clinical trials

REVERSE

NCT02521311

Hereditary retinal disease

RECOVER

NCT03406104

Leber Hereditary Optic Neuropathy (LHON), Pediatric clinical trials

RESCUE/REVERSE



Pediatric Ophthalmology Rare Diseases (WG3)



Low Vision, Daily Life and Patients Groups (TWG5)



Genetic Diagnostics (TWG6)



Registries & Epidemiology (TWG7)



Research (TWG8)



Education, Training and Guideline Frame (TWG9)



Communication, Management & Quality (TWG10)



ePag



ERN-EYE Coordinating committee



BBS Guidelines

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